程超,男,主任醫(yī)師,胸外科教授。
醫(yī)療特長:
多年來致力于肺癌、食管癌、胸腺瘤、重癥肌無力等以外科為主的多學(xué)科綜合治療和轉(zhuǎn)化性研究。擅長上述多個病種的規(guī)范化診治及微創(chuàng)手術(shù)治療。善于挑戰(zhàn)胸外科的高難手術(shù),如之前成功完成的胸第一肋動脈瘤樣骨囊腫得到國際同行的好評并在胸外科國際一流期刊ATS發(fā)表,成功完成89歲高齡的食管癌根治術(shù)并獲得較好療效,在我科率先開展了肺癌袖式切除術(shù)等。
研究方向:
多年來致力于肺癌、食管癌、胸腺瘤、重癥肌無力等以外科為主的多學(xué)科綜合治療和轉(zhuǎn)化性研究。目前主持包括兩項國家自然基金在內(nèi)的多項科研項目經(jīng)費逾100萬,近幾年在oncotarget, molecular pharmacology therapeutics, ATS等雜志發(fā)表20余篇SCI論文。
主要教育和工作經(jīng)歷:
教育經(jīng)歷:
1992-1997,中山醫(yī)科大學(xué)臨床專業(yè)本科畢業(yè),獲學(xué)士學(xué)位;
1997-1999,中山大學(xué)附一院外科七年制碩士畢業(yè),獲外科碩士學(xué)位;
2002-2005,中山大學(xué)腫瘤學(xué)博士畢業(yè),獲博士學(xué)位;
工作經(jīng)歷:
2001年獲聘主治醫(yī)生。
2007年晉升副教授。
2009年任胸外科副主任,主管科室科研教學(xué)工作。
社會兼職:兼任廣東省胸部腫瘤防治研究會副主任委員,廣東省醫(yī)療行業(yè)協(xié)會胸外科分會副主任委員,廣東省肺癌中青年專業(yè)委員會常委,中國抗癌協(xié)會會員,國際胸外科協(xié)會會員,國際肺癌專業(yè)委員會會員等,國家自然科學(xué)基金評審專家。是胸外科國際一流期刊ATS,MP,cell transplantation等多個權(quán)威雜志特邀審稿人。
論著:
1. Junmou Hong; Zhenguo Liu; Hua zhu; Xin Zhang; Yongju Liang ;Shiyuan Yao; Fang Wang; Xiaoyun xie; Bo Zhang; Tao Tan; Liwu Fu; Jing Nie;Chao Cheng.The Tumor Suppressive Role of NUMB isoform 1 in Esophageal Squamous Cell Carcinoma. Oncotarget 2014 jul 30;5(14):5602-14. (corresponding author 2013 IF=6.636).
2. Lai YR,Hong JM,Deng ZS,Yeung SC,*Cheng C. Bilateral pulmonary atery aneurysms, coronary atery aneurysm, and ventricular pseudoaneurysm in Behcet disease. Ann vasc surg, 28(3), pp 741.e7-e741, 2013/10/24
3. Chao Cheng, Zhen-guo Liu, , Zhang H, Xie JD, Chen XG, Zhao XQ, Wang F, Liang YJ, Chen LK, Singh S, Chen JJ, Talele TT, Chen ZS, Zhong FT, Fu LW.Enhancing chemosensitivity in ABCB1- and ABCG2-Overexpressing Cells and Cancer Stem-Like Cells by An Aurora Kinase Inhibitor CCT129202. Mol Pharmaceutics.2012, 9 (7),1971–1982 (IF: 5.4 , 2010)
4.Cheng C,Liu Z, Xu F, Deng Z, Feng H, Lei Y, Zou J, Yeung SC. Clinical outcome of juvenile myasthenia gravis after extended transsternal thymectomy in a chinese cohort. Ann Thorac Surg. 2013 Mar;95(3):1035-41. (IF: 3.8 , 2010)..
5. Liu Z, Feng H, Yeung SC, Zheng Z, Liu W, Ma J, Zhong FT, Luo H, Cheng C. Extended transsternal thymectomy for the treatment of ocular myasthenia gravis. Ann Thorac Surg 2011; 92: 1993-9 (通訊作者) (IF: 3.8 , 2010)
6. Can-qiao Luo, Sai-Ching J. Yeung, Zhen-guo Liu, Jun Meng, Fo-tian Zhong, Chao Cheng. Pulmonary well-differentiated Fetal Adenocarcinoma with Platelet-Derived Growth Factor Receptor (PDGFR)α Expression. Cancer biol ther. 2012 ,13(14):1384-9. (通訊作者) (IF: 2.9 , 2010)
7. Cheng C, Wu G, Yeung SC, Li R, Bella AE, Pang J, Zhong FT, Luo H, Jin Y, Pan J. Serum Protein Profiles in Myasthenia Gravis. Annal of thoracic surgery. 2009, 88(4):1118-23. (IF: 3.8 , 2010)
8. Cheng C, Yeung SC, Zhong FT, Xiong Y, Luo HH, Ji S, Pan J.The aneurysmal bone cyst in the first rib: report of two cases. Annal of thoracic surgery. 2008,85(6):2118-2120. (IF: 3.8 , 2010)
9. Cheng Chao, Amos Ela Bella, Guo Ai-lin, Wu Guo-yong. Detection of PRL-2 Gene Expression in Hepatocellular Carcinoma by Real-time Fluorescence Quantitative PCR. J ournal of Chinese –German clinical Oncology. 2009,8(4):210-213.
10. Pan J, Cheng C, Verstovsek S, Chen Q, Jin Y, Cao Q. The BH3-mimetic GX15-070 induces autophagy, potentiates the cytotoxicity of carboplatin and 5-fluorouracil in esophageal carcinoma cells.Cancer letter,2010, 293(2):167-74. (IF: 4.2 , 2010)
11. Wen-jing zhou,Xu Zhang,Chao Cheng,Fang Wang,Xiao-kun Wang,Yong-ju Liang, Li-wu Fu.Crizotinib(PF-02341066) reverses multidrug resistance in cancer cells by inhibiting the function of P-glycoprotein. Brit J Pharmacol.2012 Jul;166(5):1669-83. (IF: 4.925 , 2010)
12. Shi X, Jin Y, Cheng C, Zhang H, Zou W, Zheng Q, Lu Z, Chen Q, Lai Y, Pan J. Triptolide inhibits Bcr-Abltranscription and induces apoptosis in STI571-resistant chronic myelogenous leukemia cells harboring T315I mutation . Clinical Cancer Research. 2009,15(5):1686-97. (IF: 7.7 , 2010)
13. Pan J, Song E, Cheng C, Lee MH, Yeung SC. Farnesyltransferase inhibitors-induced autophagy. Autophagy 2009, 5(1) :129-131. (IF: 7.5 , 2010)
14. Wu GY, Pang JZ, Cheng C, Lu JJ, Ma J, Gu Y, Zhong FT, Luo HH. Prognosis of the short-term efficacy of thymectomy for myasthenia gravis with serum protein profiles. Chin Med J (Engl). 2009 ,122(14):1625-30. (IF: 0.98 , 2010)
15. Jin Y, Chen Q, Shi X, Lu Z, Cheng C, Lai Y, Zheng Q, Pan J. Activity of Triptolide against human mast cells harboring the kinase domain mutant KIT. Cancer Science.2009,100(7):1335-43. (IF: 3.3 , 2010)
16. Lin S, Liu K, Wu W, Chen C, Wang Z, Zhang X. Study on Pretreatment of FPS-1 in Rats with Hepatic Ischemia-Reperfusion Injury. American Journal of Chinese Medicine 2009;37(2)323 – 337. (IF: 1.8 , 2010)
17. Zhiwei Xu; Shiqing Lin; Wu weikang; Hongmei Tan; Zhi Wang; Chao Cheng; Lihe Lu; Xuanhong Zhang.Growth hormone releasing peptide (ghrelin) inhibits doxorubicin induced cardiotoxicity through mitochondria mediated pathways. Toxicology.2008;21:247(2-3):133-138. (SCI,2007 IF: 2.919)
專著:
1.《腫瘤磁感應(yīng)治療》,唐勁天主編,人民衛(wèi)生出版社,2009年5 月。熱刺激對腫瘤細(xì)胞的殺傷作用章節(jié)。148-158,約1 萬字。參編
2.《外科病理生理學(xué)》,譚基明主編,人民衛(wèi)生出版社,2009年2 月。免疫與外科疾病章節(jié)。598-623,約2.63萬字。參編
3.《自噬-生物學(xué)與疾病》,秦正紅、樂衛(wèi)東主編,科學(xué)出版社,2010年3月。自噬與異常蛋白折疊章節(jié)。116-134,約1.45萬字。參編
4.《臨床診斷與治療方案》分冊,王深明主編,科學(xué)技術(shù)文獻出版社,胸心血管外科疾病臨床診斷與治療方案多個章節(jié),2010年,約5.7萬字。參編
5. 《細(xì)支氣管肺泡癌》,吳一龍主審,人民衛(wèi)生出版社,細(xì)支氣管肺泡癌的分子靶向治療,2009年1月,131-149,約1.51萬字,參編