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趙建寧
三甲
主任醫(yī)師|教授|中國醫(yī)師協(xié)會骨科醫(yī)師分會委員
所在醫(yī)院:南京軍區(qū)總醫(yī)院
所在科室:骨科


擅長:南京市南京軍區(qū)總醫(yī)院骨科趙建寧復雜人工關節(jié)置換及翻修,股骨頭壞死診斷及治療,成人先天性髖關節(jié)脫位,關節(jié)置換術后感染,類風濕性關節(jié)炎外科治療
簡介
趙建寧,南京軍區(qū)南京總醫(yī)院骨科主任,主任醫(yī)師,教授,南京大學、第二軍醫(yī)大學、南京醫(yī)科大學和南方醫(yī)科大學博士生導師,博士后聯(lián)系導師,技術三級,文職一級,享受國務院政府特殊津貼和軍隊優(yōu)秀人才特殊津貼。江蘇省有突出貢獻中青年專家,榮立三等功2次。 全軍骨科專業(yè)委員會副主任委員、關節(jié)外科主任委員,全國關節(jié)外科委員,髖關節(jié)外科工作委員會執(zhí)委,副組長, 膝關節(jié)外科工作委員會委員,全國和全軍殘疾人學會肢體殘疾委員會副主任委員,中國醫(yī)師協(xié)會骨科專業(yè)委員,關節(jié)外科常務委員,全軍運動醫(yī)學及關節(jié)鏡學會委員,中國老年學會脊柱關節(jié)疾病專業(yè)委員會常務委員,華裔骨科學會理事,亞太人工關節(jié)學會中國分會理事。江蘇省和南京市骨科專業(yè)副主任委員,江蘇省中西醫(yī)結合學會骨傷專業(yè)副主任委員,南京軍區(qū)顯微外科專業(yè)主任委員,南京軍區(qū)骨科專業(yè)副主任委員等。并擔任《醫(yī)學研究生學報》副主編、《中華創(chuàng)傷骨科雜志》、《中國骨與關節(jié)損傷雜志》、《中國矯形外科雜志》、《中國骨傷》、《中華解剖與臨床》、《The Jourmai of Arthroplasty》中文版雜志等雜志的常務編委和編委。 主要研究方向為人工關節(jié)置換術后無菌性松動的防治和關節(jié)軟骨損傷的早期診斷和修復。獲國家自然科學基金等課題9項,省部級科技進步獎14項,其中二等獎6項,獲國家專利6項,主譯或參與編寫專著6部,以第一和通訊作者發(fā)表論文300余篇,其中SCI論文42篇,總影響因子104.527,最高影響因子11.753。至今已培養(yǎng)25名博士生,已畢業(yè)15名,54名碩士生畢業(yè)。 2016年擬招收1-2名博士后,要求博士年齡30歲以下。 近5年科研情況匯總 SCI文章 序號 論文題目 雜志名稱 作者 發(fā)表 年月 卷 期 頁碼 1 Autophagy mediated CoCrMo particle-induced peri-implant osteolysis by promoting osteoblast apoptosis Autophagy IF 11.753 趙建寧 2015 11 12 2358 - 2369 2 Polymorphisms in TP53 are associated with risk and survival of osteosarcoma in a Chinese population International Journal of Clinical and Experimaental Pathology IF 1.891 趙建寧 2015 8 3 3198-3203 3 The fibroblast expression of RANKL in CoCrMO-Particle-induced osteolysis is mediated by ER stress and XBP1s Acta biomaterialia IF 6.025 趙建寧 2015 24 352-360 4 ER stress mediated TiAl6V4 particle-induced peri-implant osteolysis by promoting RANKL expression in fibroblasts Plos One IF 3.234 趙建寧 2015 10 9 e0137774 5 Expression of XBP1s in Fibroblasts is Critical for TiAl6V4 Particle-Induced RANKL Expression and Osteolysis Journal of Orthopaedic Research IF 2.986 趙建寧 2015 ONLINE 6 Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism Int J Clin Exp Pathol IF 1.891 趙建寧 2015 8 5 5044-5052 7 The flavonoid ampelopsin inhibited cell growth and induced apoptosis and G0/G1 arrest in human osteosarcoma MG-63 cells in vitro Pharmazie IF 1.052 趙建寧 2015 70 6 388-393 8 Tumor necrosis factor-like weak inducer of apoptosis regulates particle-induced inflammatory osteolysis via the p38 mitogen-activated protein kinase signaking pathway Molecular medicine reports IF 1.554 趙建寧 2015 12 1 1499-1505 9 Inhibition of Microtubule Dynamics Affects Podosome Belt Formation During Osteoclast Induction Cell Biochemistry and Biophysics IF 1.68 趙建寧 2015 71 2 741-747 10 Expression and clinical significance of cyclooxygenase-2 and microRNA-143 in osteosarcoma Experimental and therapeutic medicine IF 1.269 趙建寧 2015 9 6 2374-2378 11 A single nucleotide polymorphism in the TGF-B1 gene(rs1982073C>T)may contribute to increased risks of bone fracture,osteoporosis,and osteoarthritis:a meta-analysis Clin rheumatol IF 1.696 趙建寧 2014 36 3 2059-2064 12 Exchanging reamed nailing versus augmentative compression plating with autogenous bone grafting for aseptic femoral shaft nonunion: A retrospective cohort study Editorial Manager IF 0.614 趙建寧 2015 49 6 668-675 13 Osteoprotective effect of combination therapy of low-dose oestradiol with G15, a specific antagonist of GPR30/GPER in ovariectomy-induced osteoporotic rats Bioscience Reports IF 2.637 趙建寧 2015 35 4 94-100 14 Endoplasmic reticulum stress-mediated inflammatory signaling pathways within the osteolytic periosteum and interface membrane in particle-induced osteolysis Cell and Tissue Research IF 3.565 趙建寧 2015 15 Anxiolytic-like effects of translocator protein (TSPO) ligand ZBD-2 in an animal model of chronic pain Molecular pain IF 3.654 趙建寧 2015 16 Osteoprotective effects of estrogen membrane receptor GPR30 in ovariectomized rats The journal of steroid Biochemistry and Molecular Bioiogy IF 3.628 趙建寧 2015 154 237-244 17 Associations of poiymorphisma in the bone morphogenetic protein-2 gene with risk and prognosis of osteosarcoma in a Chinese population Tumor Bio IF 3.611l 趙建寧 2015 36 3 2059-2064 18 Comparing Accuracy of Cervical Pedicle Screw placement between a Guidance System and Manual Manipulation:A Cadaver study Med Sci Monit IF 1.433 趙建寧 2015 21 2672-2677 19 Sox4 enhances chondrogenic differentiation and proliferation of human synovium-derived stem cell via activation of long noncoding RNA DANCR Journal of Molecular Histology IF 1.815 趙建寧 2015 46 6 467-473 20 Tumor-Suppressing Effects of miR-141 in Human Osteosarcoma Cell Biochemistry and Biophysics IF2.38 趙建寧 2014 69 319-325 21 Tumor- Suppressing Effects of miR-451 in Human Osteosarcoma Cell Biochemistry and Biophysics IF2.38 趙建寧 2014 70 215-224 22 Down-Regulation of miR-3928 Promoted Osteosarcoma Growth Cell Biochemistry and Biophysics IF2.38 趙建寧 2014 69 163-168 23 Learning Curve of Full-Endoscopic Technique Through Interlaminar Approach for L5/S1 DISK herniations Cell Biochemistry and Biophysics IF2.38 趙建寧 2014 33 1547-1556 24 Expression of Matrix Metalloproteinases is Positively Related to the Severity of Disc Degeneration and Growing Age in the East Asian Lumbar Disc Herniation Patients Cell Biochemistry and Biophysics IF2.38 趙建寧 2014 18 1069-1072 25 Quantitative Assessment of the Association Between HDMX Polymorphism and Sarcoma Cell Biochemistry and Biophysics IF2.38 趙建寧 2014 15 8577-8579 26 Correlation of Matrix Metalloproteinases-1 and Tissue Inhibitor of Metalloproteinases-1 with Patient Age and Grade of Lumbar Disk Herniation Cell Biochemistry and Biophysics IF2.38 趙建寧 2014 70 1219-1225 27 Research Progress on the Livin Gene and Osteosarcomas Asian Pacific Journal of Cancer Prevention IF1.5 趙建寧 2014 70 1671-1676 28 Tumor- Suppressing Effects of miR-429 on Human Osteosarcoma Cell Biochemistry and Biophysics IF2.38 趙建寧 2014 69 439-444 29 Down-Regulation of Adiponectin Receptors in Osteoarthritic Chondrocytes Cell Biochem Biophys IF2.38 趙建寧 2014 70 491-497 30 MiR-143 inhibits EGFR-signaling-dependent osteosarcoma invasion Tumor Biol IF2.84 趙建寧 2014 35 12743-12748 31 Particle-induced osteolysis mediated by endoplasmic reticulum stress in prosthesis loosening BIOMATERIALS IF 8.312 趙建寧 2013 34 11 2611-2623 32 Reply to comment on Bao et al.: Lesser trochanteric osteotomy in total hip arthroplasty for treating CROWE type IV developmental dysplasia of hip INTERNATIONAL ORTHOPAEDICS IF 2.319 趙建寧 2013 37 5 987-987 33 Lesser trochanteric osteotomy in total hip arthroplasty for treating CROWE type IV developmental dysplasia of hip INTERNATIONAL ORTHOPAEDICS IF2.319 趙建寧 2013 37 3 385-390 34 Free fatty acids are responsible for the hidden blood loss in total hip and knee arthroplasty Medical Hypotheses IF 1.054 趙建寧 2013 3 104-107 35 Significant pathways detection in Osteoporosis based on the bibliometric network EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES IF1.093 趙建寧 2013 17 1 1-7 36 MicroRNAs in osteosarcoma: From biological players to clinical contributors, a review JOURNAL OF INTERNATIONAL MEDICAL RESEARCH IF0.958 趙建寧 2013 41 1 1-12 37 Design and preliminary biomechanical analysis of artificial cervical joint complex Archivesof orthopaedlc and traumasurgery IF1.358 趙建寧 2013 133 6 735-743 38 The canonical Wnt-beta-catenin pathway in development and chemotherapy of osteosarcoma Frontiers in Bioscience IF3.286 趙建寧 2013 6 1 1384-1391 39 CaMKII activates ASK1 to induce apoptosis of spinal astrocytes under oxygen-glucose deprivation Cellular and molecular neuroblology IF 0.98 趙建寧 2013 33 4 543-549 40 Systematic screen with kinases inhibitors reveala kinases play distinct roles in growth of osteoprogenitor cells Int J Clin Exp pathol IF 2.242 趙建寧 2013 6 10 2082-2091 41 Simultaneous regeneration of articular cartilage and subchondral bone in vivo using MSCs induced by a spatially controlled gene delivery system in bilayered integrated scaffolds Biomaterials IF8.312 趙建寧 2011 3 4 科研課題 序號 項目名稱 項目來源 經(jīng)費(萬) 完成人 起止時間 1 磨損微粒誘導的成骨細胞自噬在關節(jié)假體周圍無菌性松動發(fā)病中的作用及機制研究81572111 國家自然科學基金 57 趙建寧 2016.1-2019.12 2 內(nèi)質(zhì)網(wǎng)應激抑制劑4-Phenylbutyrate(4-PBA)減輕磨損微粒誘導骨溶解的機制研究 南京市科研課題 5 趙建寧 2014.1-2017.1 3 江蘇省骨科臨床研究中心 江蘇省科技廳 150 趙建寧 2012.5-2015.12 4 抗假體松動骨水泥的研制及其抑制關節(jié)置換后骨溶解中的作用 江蘇省自然基金 10 趙建寧 2012.7-2015.6 5 抗假體松動骨水泥的研制及其抑制關節(jié)置換后骨溶解的機制研究 軍區(qū)重點課題 20 趙建寧 2012.1-2014.12
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