趙建寧,南京軍區(qū)南京總醫(yī)院骨科主任,主任醫(yī)師,教授,南京大學、第二軍醫(yī)大學、南京醫(yī)科大學和南方醫(yī)科大學博士生導師,博士后聯(lián)系導師,技術三級,文職一級,享受國務院政府特殊津貼和軍隊優(yōu)秀人才特殊津貼。江蘇省有突出貢獻中青年專家,榮立三等功2次。
全軍骨科專業(yè)委員會副主任委員、關節(jié)外科主任委員,全國關節(jié)外科委員,髖關節(jié)外科工作委員會執(zhí)委,副組長, 膝關節(jié)外科工作委員會委員,全國和全軍殘疾人學會肢體殘疾委員會副主任委員,中國醫(yī)師協(xié)會骨科專業(yè)委員,關節(jié)外科常務委員,全軍運動醫(yī)學及關節(jié)鏡學會委員,中國老年學會脊柱關節(jié)疾病專業(yè)委員會常務委員,華裔骨科學會理事,亞太人工關節(jié)學會中國分會理事。江蘇省和南京市骨科專業(yè)副主任委員,江蘇省中西醫(yī)結合學會骨傷專業(yè)副主任委員,南京軍區(qū)顯微外科專業(yè)主任委員,南京軍區(qū)骨科專業(yè)副主任委員等。并擔任《醫(yī)學研究生學報》副主編、《中華創(chuàng)傷骨科雜志》、《中國骨與關節(jié)損傷雜志》、《中國矯形外科雜志》、《中國骨傷》、《中華解剖與臨床》、《The Jourmai of Arthroplasty》中文版雜志等雜志的常務編委和編委。
主要研究方向為人工關節(jié)置換術后無菌性松動的防治和關節(jié)軟骨損傷的早期診斷和修復。獲國家自然科學基金等課題9項,省部級科技進步獎14項,其中二等獎6項,獲國家專利6項,主譯或參與編寫專著6部,以第一和通訊作者發(fā)表論文300余篇,其中SCI論文42篇,總影響因子104.527,最高影響因子11.753。至今已培養(yǎng)25名博士生,已畢業(yè)15名,54名碩士生畢業(yè)。
2016年擬招收1-2名博士后,要求博士年齡30歲以下。
近5年科研情況匯總
SCI文章
序號
論文題目
雜志名稱
作者
發(fā)表
年月
卷
期
頁碼
1
Autophagy mediated CoCrMo particle-induced
peri-implant osteolysis by promoting osteoblast
apoptosis
Autophagy
IF 11.753
趙建寧
2015
11
12
2358 - 2369
2
Polymorphisms in TP53 are associated with risk and survival of osteosarcoma in a Chinese population
International Journal of Clinical and Experimaental Pathology
IF 1.891
趙建寧
2015
8
3
3198-3203
3
The fibroblast expression of RANKL in CoCrMO-Particle-induced osteolysis is mediated by ER stress and XBP1s
Acta biomaterialia
IF 6.025
趙建寧
2015
24
352-360
4
ER stress mediated TiAl6V4 particle-induced peri-implant osteolysis by promoting RANKL expression in fibroblasts
Plos One
IF 3.234
趙建寧
2015
10
9
e0137774
5
Expression of XBP1s in Fibroblasts is Critical for TiAl6V4 Particle-Induced RANKL Expression and Osteolysis
Journal of Orthopaedic Research
IF 2.986
趙建寧
2015
ONLINE
6
Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism
Int J Clin Exp Pathol
IF 1.891
趙建寧
2015
8
5
5044-5052
7
The flavonoid ampelopsin inhibited cell growth and induced apoptosis and G0/G1 arrest in human osteosarcoma MG-63 cells in vitro
Pharmazie
IF 1.052
趙建寧
2015
70
6
388-393
8
Tumor necrosis factor-like weak inducer of apoptosis regulates particle-induced inflammatory osteolysis via the p38 mitogen-activated protein kinase signaking pathway
Molecular medicine reports
IF 1.554
趙建寧
2015
12
1
1499-1505
9
Inhibition of Microtubule Dynamics Affects Podosome Belt Formation During Osteoclast Induction
Cell Biochemistry and Biophysics
IF 1.68
趙建寧
2015
71
2
741-747
10
Expression and clinical significance of cyclooxygenase-2 and microRNA-143 in osteosarcoma
Experimental and therapeutic medicine
IF 1.269
趙建寧
2015
9
6
2374-2378
11
A single nucleotide polymorphism in the TGF-B1 gene(rs1982073C>T)may contribute to increased risks of bone fracture,osteoporosis,and osteoarthritis:a meta-analysis
Clin rheumatol IF 1.696
趙建寧
2014
36
3
2059-2064
12
Exchanging reamed nailing versus augmentative compression plating with autogenous bone grafting for aseptic femoral shaft nonunion: A retrospective cohort study
Editorial Manager
IF 0.614
趙建寧
2015
49
6
668-675
13
Osteoprotective effect of combination therapy of low-dose oestradiol with G15, a specific antagonist of GPR30/GPER in ovariectomy-induced osteoporotic rats
Bioscience Reports
IF 2.637
趙建寧
2015
35
4
94-100
14
Endoplasmic reticulum stress-mediated inflammatory signaling
pathways within the osteolytic periosteum and interface
membrane in particle-induced osteolysis
Cell and Tissue Research
IF 3.565
趙建寧
2015
15
Anxiolytic-like effects of translocator protein
(TSPO) ligand ZBD-2 in an animal model of
chronic pain
Molecular pain IF 3.654
趙建寧
2015
16
Osteoprotective effects of estrogen membrane receptor GPR30 in ovariectomized rats
The journal of steroid Biochemistry and Molecular Bioiogy
IF 3.628
趙建寧
2015
154
237-244
17
Associations of poiymorphisma in the bone morphogenetic protein-2 gene with risk and prognosis of osteosarcoma in a Chinese population
Tumor Bio IF 3.611l
趙建寧
2015
36
3
2059-2064
18
Comparing Accuracy of Cervical Pedicle Screw placement between a Guidance System and Manual Manipulation:A Cadaver study
Med Sci Monit
IF 1.433
趙建寧
2015
21
2672-2677
19
Sox4 enhances chondrogenic differentiation and proliferation of human synovium-derived stem cell via activation of long noncoding RNA DANCR
Journal of Molecular Histology IF 1.815
趙建寧
2015
46
6
467-473
20
Tumor-Suppressing Effects of miR-141 in Human Osteosarcoma
Cell Biochemistry and Biophysics IF2.38
趙建寧
2014
69
319-325
21
Tumor- Suppressing Effects of miR-451 in Human Osteosarcoma
Cell Biochemistry and Biophysics IF2.38
趙建寧
2014
70
215-224
22
Down-Regulation of miR-3928 Promoted Osteosarcoma Growth
Cell Biochemistry and Biophysics IF2.38
趙建寧
2014
69
163-168
23
Learning Curve of Full-Endoscopic Technique Through Interlaminar Approach for L5/S1 DISK herniations
Cell Biochemistry and Biophysics IF2.38
趙建寧
2014
33
1547-1556
24
Expression of Matrix Metalloproteinases is Positively Related to the Severity of Disc Degeneration and Growing Age in the East Asian Lumbar Disc Herniation Patients
Cell Biochemistry and Biophysics IF2.38
趙建寧
2014
18
1069-1072
25
Quantitative Assessment of the Association Between HDMX Polymorphism and Sarcoma
Cell Biochemistry and Biophysics IF2.38
趙建寧
2014
15
8577-8579
26
Correlation of Matrix Metalloproteinases-1 and Tissue Inhibitor of Metalloproteinases-1 with Patient Age and Grade of Lumbar Disk Herniation
Cell Biochemistry and Biophysics IF2.38
趙建寧
2014
70
1219-1225
27
Research Progress on the Livin Gene and Osteosarcomas
Asian Pacific Journal of Cancer Prevention IF1.5
趙建寧
2014
70
1671-1676
28
Tumor- Suppressing Effects of miR-429 on Human Osteosarcoma
Cell Biochemistry and Biophysics IF2.38
趙建寧
2014
69
439-444
29
Down-Regulation of Adiponectin Receptors in Osteoarthritic Chondrocytes
Cell Biochem Biophys
IF2.38
趙建寧
2014
70
491-497
30
MiR-143 inhibits EGFR-signaling-dependent osteosarcoma invasion
Tumor Biol IF2.84
趙建寧
2014
35
12743-12748
31
Particle-induced osteolysis mediated by endoplasmic reticulum stress in prosthesis loosening
BIOMATERIALS
IF 8.312
趙建寧
2013
34
11
2611-2623
32
Reply to comment on Bao et al.: Lesser trochanteric osteotomy in total hip
arthroplasty for treating CROWE type IV developmental dysplasia of hip
INTERNATIONAL ORTHOPAEDICS
IF 2.319
趙建寧
2013
37
5
987-987
33
Lesser trochanteric osteotomy in total hip arthroplasty for treating CROWE type IV developmental dysplasia of hip
INTERNATIONAL ORTHOPAEDICS IF2.319
趙建寧
2013
37
3
385-390
34
Free fatty acids are responsible for the hidden blood loss in total hip and knee arthroplasty
Medical Hypotheses
IF 1.054
趙建寧
2013
3
104-107
35
Significant pathways detection in Osteoporosis based on the bibliometric network
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES IF1.093
趙建寧
2013
17
1
1-7
36
MicroRNAs in osteosarcoma: From biological players to clinical contributors, a review
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH IF0.958
趙建寧
2013
41
1
1-12
37
Design and preliminary biomechanical analysis of artificial cervical joint complex
Archivesof orthopaedlc and traumasurgery IF1.358
趙建寧
2013
133
6
735-743
38
The canonical Wnt-beta-catenin pathway in development and chemotherapy of osteosarcoma
Frontiers in Bioscience IF3.286
趙建寧
2013
6
1
1384-1391
39
CaMKII activates ASK1 to induce apoptosis of spinal astrocytes under oxygen-glucose deprivation
Cellular and molecular neuroblology IF 0.98
趙建寧
2013
33
4
543-549
40
Systematic screen with kinases inhibitors reveala kinases play distinct roles in growth of osteoprogenitor cells
Int J Clin Exp pathol
IF 2.242
趙建寧
2013
6
10
2082-2091
41
Simultaneous regeneration of articular cartilage and subchondral bone in vivo using MSCs induced by a spatially controlled gene delivery system in bilayered integrated scaffolds
Biomaterials IF8.312
趙建寧
2011
3
4
科研課題
序號
項目名稱
項目來源
經(jīng)費(萬)
完成人
起止時間
1
磨損微粒誘導的成骨細胞自噬在關節(jié)假體周圍無菌性松動發(fā)病中的作用及機制研究81572111
國家自然科學基金
57
趙建寧
2016.1-2019.12
2
內(nèi)質(zhì)網(wǎng)應激抑制劑4-Phenylbutyrate(4-PBA)減輕磨損微粒誘導骨溶解的機制研究
南京市科研課題
5
趙建寧
2014.1-2017.1
3
江蘇省骨科臨床研究中心
江蘇省科技廳
150
趙建寧
2012.5-2015.12
4
抗假體松動骨水泥的研制及其抑制關節(jié)置換后骨溶解中的作用
江蘇省自然基金
10
趙建寧
2012.7-2015.6
5
抗假體松動骨水泥的研制及其抑制關節(jié)置換后骨溶解的機制研究
軍區(qū)重點課題
20
趙建寧
2012.1-2014.12