宮曄,男,主任醫(yī)師,教授,博士研究生導(dǎo)師,神經(jīng)外科副主任 專長:專長于各類顱腦腫瘤,尤其各類重要功能區(qū)腦膜瘤、惡性腦膜瘤、多次復(fù)發(fā)腦膜瘤、腦膜肉瘤、血管外皮瘤以及前中 顱底腫瘤 、鞍區(qū)腫瘤、神經(jīng)鞘瘤、膠質(zhì)瘤和 腦積水 、 腦外傷 、腦出血的現(xiàn)代神經(jīng)外科顯微微創(chuàng)手術(shù)及術(shù)后綜合治療方案應(yīng)用。 研究經(jīng)歷: 復(fù)旦大學(xué)華山醫(yī)院神經(jīng)外科碩士、博士畢業(yè);2002.9至2004.1在美國密西根大學(xué)進(jìn)修神經(jīng)外科并作博士后研究工作;先后主持腦膜瘤、腦出血相關(guān)國家自然科學(xué)基金3項,指導(dǎo)1項;主持上海市科委重點專項腦膜瘤研究2項;曾獲華山醫(yī)院優(yōu)秀歸國人員一等獎、“優(yōu)秀華山人”稱號、上海醫(yī)學(xué)科技獎三等獎等多項獎項。 2009年至今,負(fù)責(zé)神經(jīng)外科腦膜瘤、血管外皮瘤基礎(chǔ)和臨床研究,以及前中 顱底腫瘤 微創(chuàng)手術(shù)治療研究方向的亞??平ㄔO(shè);先后參加德國美因茨大學(xué)(Perneczky)神經(jīng)內(nèi)窺鏡keyhole微創(chuàng)手術(shù)學(xué)習(xí)班、瑞士AO顱底外科學(xué)習(xí)班、德國Maniz顱底外科及美國鳳凰城(Barrow)顱底外科學(xué)習(xí)班。曾作為訪問學(xué)者在美哈佛大學(xué)麻省總院(MGH)、匹茲堡大學(xué)醫(yī)院(UPMC)及梅奧臨床醫(yī)學(xué)中心(Mayo Clinic)神經(jīng)外科進(jìn)行臨床交流,研究顱底外科微創(chuàng)及內(nèi)鏡手術(shù)技術(shù)。 在美國神經(jīng)外科醫(yī)師協(xié)會年會(AANS Meeting)、世界神經(jīng)外科聯(lián)盟大會(WFNS Meeting)、神經(jīng)外科醫(yī)師年會(CNS Meeting)、神經(jīng)科學(xué)年會(Neuroscience Meeting)、腦出血年會(ICH Meeting)及世界神經(jīng)腫瘤等大會上作大會發(fā)言。目前以第一作者及通訊作者身份發(fā)表英文SCI論文近30篇;另在多個國內(nèi)權(quán)威、核心期刊上發(fā)表論文20余篇。任《中國臨床神經(jīng)科學(xué)》、《中國神經(jīng)精神疾病》雜志編委、審稿人;上海醫(yī)學(xué)會神經(jīng)外科分會常委,腫瘤學(xué)組秘書;中華醫(yī)學(xué)會神經(jīng)外科分會青年委員。 發(fā)表論文: 1. Analysis of gene expression profiling in meningioma: deregulated signaling pathways associated with meningioma and EGFL6 overexpression in benign meningioma tissue and serum. PLoS One. (2012) 2. Histopathological classification and location of consecutively operated meningiomas at a single institution in China from 2001 to 2010. Chin Med J (Engl). (2013) 3. Lymphoplasmacyte-rich meningioma: our experience with 19 cases and a systematic literature review. Int J Clin Exp Med. (2013) 4. 133-Positive Cells Might Be Responsible for Efficient Proliferation of Human Meningioma Cells. Int J Mol Sci. (2012) 5. Alteration of intracellular calcium and its modulator SLC24A6 after experimental intracerebral hemorrhage. Acta Neurochir Suppl. (2013) 6. Early changes in GMRP1 after intracerebral hemorrhage: involvement in brain damage and cell apoptosis. Acta Neurochir Suppl. (2013) 7. Papillary meningioma: clinical and histopathological observations. Int J Clin Exp Pathol. (2013) 8. Clinicopathological analysis of rhabdoid meningiomas: report of 12 cases and a systematic review of the literature. World Neurosurg. (2013) 9. Intraoperative ultrasound assistance in resection of intracranial meningiomas. Chin J Cancer Res (2013) 10. Chordoid meningioma: a retrospective study of 17 cases at a single institution. Chin Med J (Engl).(2013) 11. Secretory meningiomas: clinical, radiological and pathological findings in 70 consecutive cases at one institution. Int J Clin Exp Pathol. (2013) 12. Clinicopathological analysis of metaplastic meningioma: report of 15 cases in Huashan Hospital. Chin J Cancer Res. (2013) 13. Preoperative surgical planning for intracranial meningioma resection by virtual reality. Chin Med J (Engl).(2012) 14. Clinical features and treatment of intracranial chordoid meningioma: a report of 30 cases. Histopathology. (2013) 15. Clinical features and treatment of World Health Organization grade II and III meningiomas in childhood: report of 23 cases. J Neurosurg Pediatr. (2012) 16. ZFX regulates glioma cell proliferation and survival in vitro and in vivo. J Neurooncol. (2013) 17. Protease activated receptor-1 and brain edema formation in glioma models. Acta Neurochir Suppl (2013) 18. Effects of aging on autophagy after experimental intracerebral hemorrhage. Acta Neurochir Suppl. (2011) 19. Leptin plays a role in ruptured human brain arteriovenous malformations. Acta Neurochir Suppl. (2008) 20. Increase of brain thrombin activity after experimental intracerebral hemorrhage. Acta Neurochir Suppl. (2008) 21. Effects of aging on complement activation and neutrophil influx after intracerebral hemorrhage. Acta Neurochir Suppl. (2008) 22. Systemic zinc protoporphyrin administration reduces intracerebral hemorrhage-induced brain injury. Acta Neurochir Suppl. (2006) 23. Complement inhibition attenuates brain edema and neurological deficits induced by thrombin. Acta Neurochir Suppl. ( 2005) 24. Aging enhances intracerebral hemorrhage-induced brain injury in rats. Acta Neurochir Suppl. (2005) 25. Intracerebral hemorrhage: effects of aging on brain edema and neurological deficits. Stroke. (2004)